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perfluoropropane-albumin microspheres
- Development stage
- Unknown
- Lead developer
- Xiamen LiZhuo Pharmaceutical
- Modality
- Lipid-based Nanoparticles → Nanoparticles → Drug Delivery Systems
- Administration
- Intravenous
01
Overview
**Perfluoropropane-albumin microspheres** is an albumin-shelled, gas-filled microbubble ultrasound contrast agent developed and manufactured by Xiamen Lizhuo Pharmaceutical and marketed in China as **Lidaxing**. The product consists of perfluoropropane gas enclosed in heat-denatured human albumin microsphere shells and is supplied as a freeze-dried injectable preparation. After administration, the intravascular microbubbles enhance ultrasound backscatter and nonlinear acoustic signal generation, improving visualization of blood pools and tissue perfusion rather than acting through a pharmacologic receptor. It has been approved in China for left-ventricular contrast-enhanced ultrasound, evaluated in a multicenter Phase III hysterosalpingo-contrast sonography study for fallopian-tube patency, and studied in a completed Phase II thyroid contrast-enhanced ultrasound dose-finding trial. ([pmc.ncbi.nlm.nih.gov](https://pmc.ncbi.nlm.nih.gov/articles/PMC12971349/))
- Brand names
- Lidaxing力达星
- Other names
- perfluoropropane human albumin microspheresperfluoropropane-albumin microspheres for injection注射用全氟丙烷人血白蛋白微球
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