periocline

Periocline is a topical antibiotic formulation containing minocycline hydrochloride, a semi-synthetic tetracycline-class antibiotic. It is primarily used as an adjunctive treatment in periodontal therapy, specifically for adult periodontitis. Periocline is applied directly into the periodontal pocket as an ointment or gel to reduce bacterial load and inflammation associated with gum disease. The mechanism of action involves inhibition of bacterial protein synthesis by binding to the 30S ribosomal subunit, thereby preventing the growth and proliferation of susceptible bacteria within the periodontal pocket[3][4]. Minocycline exhibits broad-spectrum antibacterial activity and is effective against many gram-positive and gram-negative organisms commonly implicated in periodontitis.

Brand names

periocline

Other names

minocycline hydrochlorideminocycline HClminocycline periodontal ointment