Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
Peripheral blood stem cells (DKMS)
- Development stage
- Unknown
- Lead developer
- DKMS
- Modality
- Stem Cell Therapies → Cell Therapies
- Administration
- Intravenous
01
Overview
Peripheral blood stem cells (PBSC) are hematopoietic progenitor cells collected from the donor's blood after mobilization (typically with G-CSF). In the context of the HAMLET trial (NCT04366206) led by DKMS gemeinnützige GmbH, these cells are used for allogeneic hematopoietic cell transplantation in patients with high-risk acute myeloid leukemia (AML), acute lymphoblastic leukemia (ALL), or myelodysplastic syndromes (MDS). The study compares outcomes between transplants from partially matched unrelated donors (MMUD) and haploidentical donors, both utilizing post-transplant cyclophosphamide (PTCy) to mitigate graft-versus-host disease (GvHD). The primary therapeutic goal is the restoration of the recipient's hematopoietic system and the induction of a graft-versus-leukemia (GvL) effect to prevent disease relapse.
- Other names
- PBSCPeripheral blood progenitor cellsHematopoietic stem cells
Beyond the preview
Go deeper on Peripheral blood stem cells (DKMS).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Peripheral blood stem cells (DKMS).