Drug intelligence / Profile preview

Pertusin

Development stage
Phase 4
Lead developer
Viola Pharm
Modality
Small Molecules
Administration
Oral
01

Overview

Pertusin is a traditional over-the-counter (OTC) cough syrup widely used in Eastern Europe and CIS countries for the symptomatic relief of respiratory conditions. It is a combination pharmaceutical product typically composed of a liquid extract of thyme (*Thymus vulgaris*) and potassium bromide. The thyme extract serves as an expectorant and mucolytic agent, which helps to thin bronchial secretions and facilitate their expulsion through ciliary stimulation. Potassium bromide acts as a mild sedative on the central nervous system, helping to suppress the cough reflex and reduce irritability. It is primarily indicated for the treatment of acute respiratory infections, bronchitis, and the symptomatic management of whooping cough.

Brand names
PertusinPertussin
Other names
Pertussin syrupSyrupus Pertussini
02

Targets

GABA-B (Gamma-aminobutyric acid receptor type B)Guanine nucleotide-binding protein G(i)/G(o) alpha subunit (Gi/o alpha)

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