Drug intelligence / Profile preview

pertussis vaccine-Public Health England-Meningococcal Group C infection-Pertussis

Development stage
Unknown
Lead developer
Parent
Modality
Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

The drug entry "pertussis vaccine-Public Health England-Meningococcal Group C infection-Pertussis" refers to the concomitant administration of a Meningococcal Group C (MenC) conjugate vaccine and an acellular pertussis-containing booster vaccine as evaluated in the "Multiboost" Phase III/IV clinical trial (NCT01423825). Conducted by Public Health England, this study assessed the immunogenicity and safety of co-administering these vaccines in adolescents aged 13-17 years to streamline the UK routine immunization schedule. The regimen involves the simultaneous but separate injection of a MenC vaccine (such as Meningitec, NeisVac-C, or Menitorix) and a pertussis-containing booster (such as Repevax or IPV-Boostrix), the latter of which also provides protection against diphtheria, tetanus, and poliomyelitis. The study aimed to determine if the immune response to each component remains robust when given together compared to separate administration.

Brand names
MeningitecNeisVac-CMenitorixRepevaxIPV-Boostrix
Other names
Concomitant MenC and Pertussis Booster in AdolescentsMeningococcal Group C vaccine + Pertussis vaccine
02

Targets

FHA (Filamentous hemagglutinin)Neisseria meningitidis group C capsular polysaccharidePRN (Pertactin)TT (Tetanus toxoid)Fimbrial antigen type 3

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