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pertussis vaccine-Universiteit Antwerpen-pertussis

Development stage
Unknown
Lead developer
University of Antwerp
Modality
Vaccines & Immunotherapeutics
01

Overview

pertussis vaccine-Universiteit Antwerpen-pertussis refers to the acellular pertussis vaccines evaluated in clinical research programs at the Universiteit Antwerpen, most notably the MAMA (Maternal Antibodies and Maternal Adiposity/Immunization) study. This research focuses on the effectiveness of maternal immunization during pregnancy in providing passive immunity to infants, particularly those born preterm. The vaccines studied are typically multicomponent acellular formulations containing purified *Bordetella pertussis* antigens, including pertussis toxoid (PT), filamentous haemagglutinin (FHA), and pertactin (PRN). The university's research specifically assesses the transplacental transfer of maternal IgG antibodies and the presence of IgA in breast milk to optimize neonatal protection strategies against pertussis before infants are eligible for their own primary vaccination series.

02

Targets

FHA (Filamentous hemagglutinin)

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