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Petrolatum + glycerin is a topical combination emollient and humectant formulation. In the clinical trial conducted by Shenzhen People's Hospital for the treatment of acne, this combination serves as a placebo control (simple moisturizing cream). Petrolatum acts as an occlusive agent, creating a physical barrier on the skin surface to prevent transepidermal water loss (TEWL). Glycerin is a humectant that attracts and binds water within the stratum corneum. Together, these ingredients aim to hydrate the skin and support barrier function, which is often compromised in inflammatory skin conditions like acne.
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