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PF-05402536
- Development stage
- Phase 1
- Lead developer
- Pfizer
- Modality
- Split/Subunit Vaccines → Inactivated Vaccines → Prophylactic Vaccines → Vaccines & Immunotherapeutics, Cancer Vaccines → Therapeutic Vaccines → Vaccines & Immunotherapeutics
- Administration
- Intramuscular
01
Overview
PF-05402536 is an investigational therapeutic vaccine developed for smoking cessation. It functions as an immunostimulant, aiming to generate an immune response against nicotine to reduce its psychoactive effects, thereby assisting smokers in quitting. The drug is classified as both a therapeutic and toxoid vaccine, targeting the nicotine molecule itself rather than a biological receptor or protein. The developer and sponsor of clinical trials is Pfizer. PF-05402536 has undergone phase 1 clinical testing for safety, tolerability, immunogenicity, and exploratory efficacy in adult smokers motivated to quit[1][3][9].
- Other names
- NIC7-001NIC-7-001NIC 7-001
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