Drug intelligence / Profile preview

PF-06413367

Development stage
Phase 1
Lead developer
Pfizer
Modality
Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

PF-06413367 is an investigational drug candidate developed by Pfizer that has been evaluated in combination with PF-05402536 as part of a vaccine immunotherapy approach for smoking cessation. It was tested in healthy adult smokers to assess its safety, tolerability, and immunogenicity. Specific mechanism of action or target information is not publicly detailed, but both drugs (PF-06413367 and PF-05402536) are referred to as "smoking vaccines," suggesting a potential immune-based modality aimed at nicotine or a related target[3][4][7]. The drug has completed Phase 1 clinical studies, and no further advanced clinical development has been publicly reported.

Other names
anti-nicotine vaccinenicotine vaccine

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