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PF-06423264

Development stage: Discontinued
Lead developer: Pfizer
Modality: Small Molecules
Administration: Oral

Overview

PF-06423264 is a small molecule inhibitor targeting acetyl-coenzyme A carboxylase (ACC) alpha and beta isoforms. It was developed by Pfizer for the treatment of acne. The drug acts by inhibiting ACC, an enzyme involved in fatty acid synthesis, which is thought to play a role in the pathogenesis of acne. Development of PF-06423264 has been discontinued[1][2][7].

Targets

ACC (Acetyl-CoA Carboxylase 1)

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