Drug intelligence / Profile preview

PF-07872444

Development stage
Unknown
Lead developer
Pfizer
Modality
Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

PF-07872444 is a pneumococcal conjugate vaccine component developed by Pfizer. It consists of a specific *Streptococcus pneumoniae* capsular polysaccharide conjugated to a carrier protein, typically CRM197. The drug is being developed as part of an expanded multivalent pneumococcal conjugate vaccine (PCV) regimen, which aims to provide broader protection than the current 20-valent vaccine (Prevenar 20) by including additional serotypes. PF-07872444 is currently being evaluated in Phase 3 clinical trials in healthy infants as one of several new conjugate components in an expanded multivalent vaccine candidate designed to prevent invasive pneumococcal disease and pneumonia.

02

Targets

CPS (Streptococcus pneumoniae capsular polysaccharide)

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