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PF-07941314
- Development stage
- Phase 1
- Lead developer
- Pfizer
- Modality
- Vaccines & Immunotherapeutics, mRNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Recombinant Proteins and Enzymes
- Administration
- Intramuscular
01
Overview
**PF-07941314** is Pfizer's investigational fixed-dose respiratory combination vaccine comprising an RSV protein-subunit vaccine component, RSVpreF, and a modified-RNA influenza vaccine component, qIRV. It was evaluated in the Phase 1 C5401001 study in older adults as 0.5 mL and 1.0 mL combined-vaccine formulations, assessing safety, tolerability, and immune responses against respiratory syncytial virus and influenza. Pfizer subsequently halted development of the early-stage RSV-influenza combination vaccine program. ([pfizer.com](https://www.pfizer.com/sites/default/files/plsr-studies/C5401001%20Plain%20Language%20Study%20Results%20Summary%20%28PLSRS%29%20Phase%201%20PK%20Primary%20Endpoint%20%28002%29.pdf))
- Other names
- RSV Subunit and Influenza modRNA Combination VaccineRSVpreF + qIRV
02
Targets
RSV F (Respiratory syncytial virus fusion protein)
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