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PFH-VAP
- Development stage
- Preclinical
- Lead developer
- Particles for Humanity
- Modality
- Nanoparticles → Drug Delivery Systems, Small Molecules
- Administration
- Oral
01
Overview
PFH-VAP is a microencapsulated nutritional fortification product developed by Particles for Humanity to address vitamin A deficiency (VAD) in low- and middle-income countries. The formulation consists of vitamin A palmitate (VAP) encapsulated within a basic methacrylate copolymer (BMC) matrix, produced as a spray-dried powder. This technology is specifically designed to stabilize vitamin A against degradation caused by heat, humidity, and light, which are prevalent in the storage conditions of hot and humid climates. PFH-VAP is intended for the fortification of staple foods and condiments, such as bouillon cubes, wheat flour, and sugar. The product has undergone commercial-scale manufacturing validation and is supported by organizations including the Bill & Melinda Gates Foundation.
- Other names
- microencapsulated vitamin A palmitatevitamin A palmitate encapsulated in basic methacrylate copolymerVAP-BMC
02
Targets
RAR (Retinoic acid receptor)
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