Drug intelligence / Profile preview

PGX

Development stage
Unknown
Lead developer
InovoBiologic Inc.
Modality
Microbiome Therapeutics
Administration
Oral
01

Overview

PGX is a soluble viscous fiber, specifically an alginate-konjac-xanthan polysaccharide complex, developed by InovoBiologic Inc. and associated with Factors Group of Companies. It is designed as an adjunct to intensive weight management programs, particularly for adults with type 2 diabetes and overweight/obesity. PGX beneficially affects metabolism by improving glycemic control (reducing HbA1c), promoting weight loss, decreasing waist circumference, and lowering LDL cholesterol. Its mechanism involves modulating gut microbiota, specifically increasing the relative abundance of beneficial bacteria such as *Collinsella*, *Parabacteroides*, and *Roseburia*, and influencing short-chain fatty acid production.

Brand names
PGXPGX®PolyGlycopleX
Other names
soluble viscous fibrenovel functional fibrenovel viscous polysaccharidealginate-konjac-xanthan polysaccharide complex

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