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PHARMAPATCH
- Development stage
- Unknown
- Lead developer
- PharmaTher
- Modality
- Small Molecules
- Administration
- Transdermal
01
Overview
PHARMAPATCH is a transdermal ketamine delivery system being developed by PharmaTher Holdings Ltd. for the management of acute postoperative and chronic pain. The patch utilizes proprietary microneedle technology to provide controlled, sustained release of ketamine, an NMDA receptor antagonist, aiming to maintain constant therapeutic plasma levels for over 24 hours while minimizing side effects associated with peak-and-trough concentrations. Developed via the FDA 505(b)(2) regulatory pathway, PHARMAPATCH is designed as a non-opioid alternative for analgesia and includes anti-tampering and anti-abuse features. Beyond pain management, the company is exploring its potential in mental health indications such as treatment-resistant depression, suicidality, and PTSD.
- Brand names
- PHARMAPATCH
- Other names
- ketamine transdermal patchtransdermal patch (ketamine)
02
Targets
NMDAR (Glutamate receptor ionotropic, NMDA)
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