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PHE1411 is an investigational therapeutic candidate being developed by Zhongke CELFULL Mitochondrial Medicine for the treatment of phenylketonuria (PKU). PKU is a rare genetic metabolic disorder characterized by a deficiency in the enzyme phenylalanine hydroxylase, which leads to the toxic accumulation of phenylalanine in the body. PHE1411 is currently in the preclinical stage of development. Although the developer focuses on mitochondrial medicine and metabolic health, specific details regarding the drug's modality (e.g., small molecule, enzyme replacement) or its exact molecular mechanism of action have not been publicly disclosed in the company's pipeline.
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