Drug intelligence / Profile preview

phellodendron bawei

Development stage
Unknown
Lead developer
Xiangya Hospital, Central South University
Modality
Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules
Administration
Oral
01

Overview

Phellodendron bawei (also known as Huangbai Bawei) is a Traditional Chinese and Mongolian Medicine formulation used primarily for the treatment of urogenital and inflammatory disorders. The formulation is characterized by the inclusion of eight medicinal ingredients (indicated by the term "Bawei"), with *Phellodendron amurense* (Amur cork tree bark) serving as the principal component. In clinical research, it is evaluated as an adjuvant therapy for patients with benign prostatic hyperplasia (BPH) to alleviate lower urinary tract symptoms (LUTS), improve sleep quality, and enhance medication compliance. Its therapeutic profile in traditional medicine involves clearing heat and drying dampness, which corresponds to anti-inflammatory and potentially prostate-modulating effects in modern clinical contexts.

Other names
Huangbai Bawei TabletsHuangbai Bawei PianPhellodendron Eight-Ingredient TabletsHuangbai Bawei Wan
02

Targets

ND1 (Mitochondrial electron transport chain complex I)Cyp (Cyclophilin family)TOP1 (DNA Topoisomerase I)

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