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pheniramine
- Development stage
- Phase 3
- Modality
- Small Molecules
- Administration
- Oral, Topical, Ophthalmic, Intravenous, Intramuscular
01
Overview
Pheniramine is a first-generation antihistamine in the alkylamine class used to treat allergic conditions such as allergic rhinitis (hay fever), urticaria (hives), pruritus (itching), and conjunctivitis. It acts primarily as an antagonist and inverse agonist at the histamine H1 receptor, blocking the effects of histamine released during allergic reactions. This reduces symptoms like itching, redness, swelling (edema), sneezing, and runny nose. Pheniramine also has anticholinergic properties that contribute to its sedative effects. It is available in oral formulations as well as topical preparations for ophthalmic use and is often found in combination with other drugs for cold or allergy relief[1][2][4][6].
- Brand names
- Naphcon AOpcon-AVisine-AAvil
- Other names
- pheniramine
02
Targets
HRH1 (Histamine H1 Receptor)HRH4 (Histamine H4 receptor)
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