phleum pratense allergen extract

**Phleum pratense allergen extract** is a standardized allergen extract derived from the pollen of *Phleum pratense* (Timothy grass), used in allergen immunotherapy to induce immune tolerance and reduce symptoms of allergic rhinitis and conjunctivitis due to grass pollen allergy. It is administered as a sublingual tablet (SLIT) or as a subcutaneous injection as part of an allergen-specific immunotherapy regimen. The extract contains a mixture of major and minor Timothy grass pollen proteins standardized for consistent potency. Its immunological action includes induction of allergen-specific blocking IgG4 antibodies, modulation of regulatory T-cells, and a shift away from the Th2-mediated allergic response, leading to long-term tolerance and symptom reduction. Primary indications are the treatment and prophylaxis of grass pollen-induced seasonal allergic rhinitis and conjunctivitis in patients with documented sensitization[^1][^3][^8].

Brand names

GrazaxGrastekOralair

Other names

Timothy grass pollen extractPhleum pratense pollenTimothyTimothy grass