phleum pratense allergoid

Phleum pratense allergoid is a chemically modified **allergen immunotherapy** product derived from *Phleum pratense* pollen, developed in the cited clinical studies by **LETI Pharma** for treatment of grass pollen allergy, particularly allergic rhinitis, rhinoconjunctivitis, and allergic asthma. The active substance is a **depigmented, glutaraldehyde-polymerized pollen extract** designed to reduce IgE-mediated allergenicity while preserving T-cell immunogenicity, enabling repeated administration by subcutaneous or intradermal injection. In randomized placebo-controlled studies, this allergoid reduced combined symptom and medication scores and improved conjunctival provocation tolerance, supporting its use as a disease-modifying allergen-specific immunotherapy rather than a symptomatic anti-allergy drug.

Brand names

Depigoid Phleum pratense

Other names

phleum pratense allergoidp. pratense allergoiddepigmented and polymerized allergen extract of phleum pratensedepigmented, polymerised extract of phleum pratense pollenglutaraldehyde-polymerized phleum pratense extractdepigmented glutaraldehyde-polymerized therapeutic vaccine of phleum pratense