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Phosphoenolpyruvate (PEP) is a high-energy phosphate compound and a crucial intermediate metabolite involved in glycolysis and gluconeogenesis. It plays a vital role in cellular energy metabolism, particularly in the production of adenosine triphosphate (ATP). Investigations have explored its therapeutic potential, demonstrating its ability to protect against ischemia-reperfusion injury and aid in organ preservation by recovering hepatic energy and preventing ATP decline. Additionally, Phosphoenolpyruvate exhibits cytoprotective and anti-oxidative properties, including the reduction of reactive oxygen species.
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