Drug intelligence / Profile preview

photocurable regenerative dermal filler

Development stage
Preclinical
Lead developer
CollPlant Biotechnologies
Modality
Recombinant Proteins and Enzymes, Hydrogel Systems → Drug Delivery Systems, Biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems
Administration
Implantation, Intradermal, Subcutaneous
01

Overview

The photocurable regenerative dermal filler is an investigational injectable product designed for use in aesthetic and reconstructive medicine. It is composed primarily of recombinant human collagen (rhCollagen) and hyaluronic acid, forming a semiliquid solution that is injected beneath the skin and then hardened *in situ* by external light illumination. This process induces polymerization, resulting in a stable implant that provides immediate lifting and sculpting effects. Uniquely, as the material degrades over time, it promotes tissue regeneration—new tissue forms to replace the degrading scaffold. The product aims to address contour deficiencies, facial lifting/sculpting, and potentially breast augmentation or reconstruction by enhancing cell proliferation and new tissue formation compared to standard fillers. The technology was developed by CollPlant Biotechnologies with a global development and commercialization agreement with Allergan Aesthetics (AbbVie). It remains under development for aesthetic indications such as facial rejuvenation[4][5][6][7].

Other names
photocurable dermal fillerrhCollagen-based photocurable dermal filler
02

Targets

α10β1 (Integrin alpha 10 beta 1)

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