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PhtE_pep40 is a peptide derived from the zinc-binding domain of the pneumococcal histidine triad protein E (PhtE). It is used in the development of epitope-based vaccines against *Streptococcus pneumoniae*, demonstrating immunogenicity and protective effects by eliciting high IgG titers and facilitating antibody-mediated killing of pneumococci[3][5].
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