Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
PHV02
- Development stage
- Phase 1
- Lead developer
- Public Health Vaccines
- Modality
- Recombinant Proteins and Enzymes, Vaccines & Immunotherapeutics
- Administration
- Intramuscular
01
Overview
PHV02 is a live, recombinant vaccine candidate designed to protect against Nipah virus infection. It utilizes a vesicular stomatitis virus (VSV) vector in which the gene for the VSV glycoprotein is replaced by the Zaire ebolavirus glycoprotein (EBOV GP), and additionally expresses the Nipah virus (NiV) attachment glycoprotein G. This chimeric construction enables the vaccine to induce an immune response targeting both Ebola and Nipah viruses, with neutralizing antibodies against NiV considered a key mediator of protection. The vaccine is administered as an intramuscular injection and has demonstrated rapid onset of protective immunity in animal models. PHV02 is currently in Phase 1 clinical trials for Henipavirus infections, including Nipah virus infection[2][4][5][7].
- Other names
- rVSV-Nipah Virus Vaccine Candidate PHV02
02
Targets
Zaire ebolavirus glycoproteinNiV-G (Nipah virus attachment glycoprotein)
Beyond the preview
Go deeper on PHV02.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on PHV02.