Drug intelligence / Profile preview

Physician EZ Use Joint Tunnel and Trigger Kit

Development stage
Unknown
Lead developer
Asclemed USA
Modality
Small Molecules
Administration
Inhalation, Intraarticular, Intramuscular, Topical
01

Overview

**Physician EZ Use Joint Tunnel and Trigger Kit** is an Asclemed USA prescription drug kit containing ammonia inhalant, lidocaine hydrochloride, povidone-iodine, and triamcinolone acetonide injectable suspension. Lidocaine provides local anesthesia through reversible voltage-gated sodium-channel blockade; povidone-iodine is used for topical antisepsis; ammonia is an inhalant irritant; and triamcinolone acetonide is a synthetic glucocorticoid with anti-inflammatory and immunosuppressive effects mediated primarily through the glucocorticoid receptor. The kit includes triamcinolone acetonide suspension intended for intramuscular or intra-articular administration and carries labeling for inflammatory, allergic, rheumatologic, dermatologic, and other corticosteroid-responsive conditions. The DailyMed label identifies Asclemed USA as packager and classifies the product as an unapproved drug other, stating that FDA has not found it safe and effective and has not approved its labeling. ([dailymed.nlm.nih.gov](https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=e25cfc22-29ba-473f-88c4-3c88e9f6863b))

Brand names
Physician EZ Use Joint Tunnel and Trigger Kit
Other names
ammonia + lidocaine hydrochloride + povidone-iodine + triamcinolone acetonide
02

Targets

SCN5A (Sodium channel protein type 5 subunit alpha)GR (Glucocorticoid receptor)MR (Mineralocorticoid receptor)NaV (Voltage-gated sodium channels)

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