Drug intelligence / Profile preview

Physiogel balanced

Development stage
Unknown
Lead developer
B. Braun
Modality
Small Molecules, Albumin → Carrier/Scaffold Proteins → Recombinant Proteins and Enzymes
Administration
Intravenous
01

Overview

Physiogel balanced is an intravenous infusion solution primarily used as a plasma substitute and volume expander. It is composed of succinylated gelatin and a balanced electrolyte solution including sodium chloride, potassium chloride, calcium chloride dihydrate, magnesium chloride hexahydrate, and sodium acetate trihydrate. The drug is indicated for the treatment of hypovolemia and shock, as well as for the prevention of hypotension during regional anesthesia or in situations involving significant blood loss during surgical procedures. Its formulation, which is lactate-free and contains acetate as a bicarbonate precursor, allows for the correction of acidosis and makes it suitable for patients with hepatic impairment. It functions by restoring lost fluid volume in both the intravascular and extravascular compartments, thereby supporting hemodynamic stability.

Brand names
Physiogel balanced
Other names
Plasma substituteInfusion solution

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