Drug intelligence / Profile preview

Phyto A+ Brightening Treatment

Development stage
Phase 4
Lead developer
SkinCeuticals
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Topical
01

Overview

Phyto A+ Brightening Treatment is a topical corrective moisturizer developed by SkinCeuticals, formulated to address skin discoloration, uneven texture, and redness. The product contains a synergistic blend of 3% azelaic acid, 2% alpha arbutin, and a 5.75% phyto-botanical complex (including cucumber, thyme, and olive leaf extracts). It functions primarily by inhibiting tyrosinase, the key enzyme in melanin synthesis, thereby reducing hyperpigmentation and improving skin clarity. The Austin Institute for Clinical Research has conducted Phase 4 clinical trials evaluating its efficacy and tolerability when used in conjunction with non-ablative laser treatments for facial dyschromia and photoaging across diverse skin types, including Fitzpatrick types I-VI and individuals of Asian descent.

Brand names
Phyto A+ Brightening TreatmentSkinCeuticals Phyto A+ Brightening Treatment
Other names
Phyto A+
02

Targets

TYR (Tyrosinase)

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