phytolacca decandra

Phytolacca decandra (synonym Phytolacca americana), commonly known as pokeweed, is a perennial plant utilized in homeopathic medicine and ethnopharmacology. In homeopathy, it is frequently administered in ultra-diluted forms (such as 12c or 12CH) for conditions including nocturnal bruxism in children, mastitis, and chronic rheumatism. Research into its phytochemical constituents, particularly triterpenoids like oleanolic acid and betulinic acid derivatives, has demonstrated potential anticancer activity in various cell lines, including melanoma, lung, and breast cancer. These effects are primarily mediated through the induction of mitochondria-dependent apoptosis, reactive oxygen species (ROS) generation, and the activation of caspase-3 signaling pathways. While traditionally used for its anti-inflammatory and lymphatic effects, the plant contains toxic alkaloids and glycoproteins, requiring careful preparation and standardized dosing in clinical applications.

Other names

Phytolacca americanapokeweedPDPhyto