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Pifubing Xuedu Wan is a traditional Chinese medicine (TCM) multi-herbal formula used primarily for the treatment of various dermatological conditions. Its main functions are to "clear blood and detoxify," reduce swelling, and relieve itching. The formula contains approximately 39 herbal ingredients, including Rubia cordifolia (茜草), Paeonia veitchii (赤芍), Kochia scoparia (地肤子), Moutan cortex (牡丹皮), Rheum palmatum processed with wine (大黄 酒炒), Smilax glabra (土茯苓), Lonicera japonica flower (金银花), Poria rubra (赤茯苓), Dictamnus dasycarpus root bark (白鲜皮), Imperata cylindrica root (白茅根), Viola yedoensis herb (苦地丁), Gleditsia sinensis thorn (皂角刺) among others[2][6][8]. It is indicated for skin diseases caused by disharmony of meridians, damp-heat, and blood dryness—such as urticaria, eczema, pruritus, acne vulgaris, rosacea-like facial redness and pustules, boils/abscesses, tinea pedis/eczema/scabies-like eruptions. It is also used for symptoms like dizziness or constipation associated with these syndromes[2][3][10]. The mechanism of action in TCM terms involves clearing heat from the blood ("liangxue"), removing toxins ("jiedu"), reducing swelling ("xiaozhong"), activating blood circulation to resolve stasis ("huoxue quyu"), and relieving itching ("zhiyang"). In Western medical terms its precise pharmacological mechanisms are not fully elucidated; it acts as a multi-target herbal combination with anti-inflammatory and immunomodulatory effects based on its components.
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