Drug intelligence / Profile preview

PIK-HER2

Development stage: Unknown
Lead developer: Naval Medical University
Modality: Adoptive Cell Transfer → Cell Therapies
Administration: Intravenous, Subcutaneous

Overview

PIK-HER2 (Pluripotent Killer-Human Epidermal Growth Factor Receptor-2) cells are a novel form of adoptive cellular immunotherapy developed by the Second Military Medical University. This biologic therapy consists of pluripotent killer T cells engineered to target the Human Epidermal Growth Factor Receptor 2 (HER2). It is specifically being evaluated for the treatment of patients with advanced HER2-positive gastric cancer, particularly those with liver metastasis. In clinical protocols, the therapy is often administered alongside dendritic cell (DC) injections to enhance the immune response. The PIK-HER2 cells are intended to induce targeted cytotoxicity against HER2-expressing tumor cells, leveraging the effector functions of the engineered T cells.

Other names: Pluripotent Killer-Human Epidermal Growth Factor Receptor-2 cellsPIK-HER2 cellsPIK-HER-2 cellsPIK-HER 2 cells

Beyond the preview

Go deeper on PIK-HER2.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Follow clinical development from study design and recruitment through results.

Trial phase
Status
Readouts

Indications & development

Explore development by indication, patient population, and geography.

Indications
Development status
Countries

Licensing & deals

Trace asset ownership, licensing agreements, and commercial partnerships.

Partners
Deal terms
Milestones

Patents & exclusivity

Explore the patent landscape and regulatory exclusivity around an asset.

Patents
Expiration dates
Exclusivity

Competitive landscape

Compare development programs by target, modality, and indication.

Competing assets
Targets
Development stage

Research & analysis

Connect source evidence and development news to your research questions.

Publications
News
Analysis

Bring the full picture into focus.

See how Gosset can support your research on PIK-HER2.

Explore the full profile