Drug intelligence / Profile preview

pinostilbene

Development stage
Preclinical
Lead developer
Long Island University
Modality
Small Molecules
Administration
Oral
01

Overview

Pinostilbene is a naturally occurring monomethylated analog of resveratrol, a polyphenol found in grapes and other plants. It is being investigated for its potential antineoplastic properties, particularly in the context of advanced prostate cancer. Research indicates that pinostilbene can inhibit the viability, proliferation, and metastatic potential of prostate cancer cells, showing significantly higher potency in more invasive cell lines compared to less invasive ones. As a derivative of resveratrol, it shares structural similarities but may offer improved bioavailability or specific activity profiles that make it a candidate for the management of lethal prostate cancer stages.

Other names
3-hydroxy-5-methoxystilbenetrans-pinostilbene5-methoxyresveratrol
02

Targets

AR (Adrenergic receptors)

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