Drug intelligence / Profile preview

PIP-2

Development stage
Unknown
Lead developer
Peroxitech
Modality
Small Molecules
01

Overview

**PIP-2** is the lead investigational compound developed by Peroxitech to address cytokine storm-induced respiratory failure in the lungs, a critical complication in severe inflammatory conditions such as acute respiratory distress syndrome (ARDS) regardless of underlying etiology like viral infections or sepsis. It targets the excessive buildup of pro-inflammatory cytokines that drive lung damage and hypoxemia, aiming to mitigate hyperinflammation and prevent progression to multi-organ failure. As an early-stage asset, its precise mechanism—potentially involving modulation of inflammatory signaling pathways or cytokine neutralization—remains proprietary, with development focused on unmet needs in critical care.

02

Targets

NOX2 (NADPH oxidase 2)PRDX6 (Peroxiredoxin-6)

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