piper guineense extract

Piper guineense extract is a botanical preparation derived from the West African pepper plant, commonly known as Uziza or Guinea pepper. It contains a complex mixture of bioactive compounds, including piperine and piperamide alkaloids, flavonoids, and tannins. The extract is primarily researched for its anti-sickling properties in the treatment of sickle cell disease, notably as a component of the phytomedicine NIPRISAN (also known as NICOSAN), developed by the National Institute for Pharmaceutical Research and Development (NIPRD) in Nigeria. Additionally, it exhibits inhibitory effects on alpha-amylase and alpha-glucosidase enzymes, suggesting potential utility in managing postprandial hyperglycemia and type 2 diabetes. Other investigated pharmacological activities include antimicrobial, antioxidant, and analgesic effects.

Other names

Uziza extractGuinea pepper extractWest African pepper extract