Drug intelligence / Profile preview

piperacillin (FUJIFILM Toyama Chemical)

Development stage
Unknown
Lead developer
FUJIFILM Toyama Chemical
Modality
Small Molecules
Administration
Intravenous, Intramuscular
01

Overview

Pentocillin is a brand name for piperacillin sodium, a broad-spectrum ureidopenicillin antibiotic developed and marketed by FUJIFILM Toyama Chemical. It is indicated for the treatment of various bacterial infections, including sepsis, pneumonia, and urinary tract infections caused by susceptible strains of Gram-positive and Gram-negative aerobic and anaerobic bacteria. Piperacillin exerts its bactericidal effect by binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, thereby inhibiting the final stage of bacterial cell wall synthesis. This leads to cell wall instability and subsequent bacterial cell lysis. Pentocillin is typically administered via intravenous or intramuscular injection and is widely used in clinical settings in Japan.

Brand names
Pentocillin
Other names
piperacillin sodiumペントシリンピペラシリンナトリウム
02

Targets

PBP2 (Penicillin-binding protein 2)PBP3 (Peptidoglycan D,D-transpeptidase FtsI)PBP2B (Penicillin-binding protein 2B)PBP1A (Penicillin-binding protein 1A)

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