Drug intelligence / Profile preview

piprinhydrinate

Development stage
Unknown
Lead developer
Kraeber
Modality
Small Molecules
Administration
Oral
01

Overview

**Piprinhydrinate** is a first-generation histamine H1-receptor antihistamine supplied as the salt of diphenylpyraline and 8-chlorotheophylline. Its clinically relevant antiallergic activity is principally mediated by diphenylpyraline antagonism of the histamine H1 receptor; 8-chlorotheophylline is a xanthine component included to mitigate antihistamine-associated sedation. Piprinhydrinate has been marketed outside the United States for allergic conditions and motion sickness. ([drugs.ncats.io](https://drugs.ncats.io/drug/SI78RFJ7XI))

Brand names
Allercon Siu GuanHCNoritle PiprinhydrinateKoltonPiprinhydrinate Hor ChenPiprinhydrinate Pei LiPiprinhydrinate Quality PharmPiprinhydrinate Yung SinePlakonPloconPlokonPlotonPrinatePrincurSumincon
Other names
8-chlorotheophyllinatediphenylpyraline 8-chlorotheophyllinatediphenylpyraline8-chlorotheophyllinatediphenylpyraline-8-chlorotheophyllinatediphenylpyraline teoclateP 284P284P-284piprinhidrinatpiprinhidrinatopiprinhydrinatepiprinhydrinatum
02

Targets

HRH1 (Histamine H1 Receptor)

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