Drug intelligence / Profile preview

piragrel sodium

Development stage
Phase 3
Lead developer
Hefei Medical and Pharmaceutical
Modality
Small Molecules
Administration
Intravenous
01

Overview

Piragrel sodium is a small molecule drug under clinical investigation as an antiplatelet agent. It is being developed primarily for the treatment of acute ischemic stroke. Piragrel sodium acts as a platelet aggregation inhibitor, similar in therapeutic intent to thienopyridine-class antiplatelet drugs, but it is chemically distinct from agents like prasugrel or clopidogrel. The drug is administered intravenously and has been evaluated in multicenter, randomized, double-blind, placebo-controlled phase II and III clinical trials for its efficacy and safety in patients with acute ischemic stroke within 48 hours of onset[6]. Its mechanism involves inhibition of platelet aggregation to reduce thrombotic events associated with cerebral infarction.

Other names
pyragrel sodium吡拉格雷钠 (Chinese name)
02

Targets

TBXAS1 (Thromboxane A2 synthase)

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