pirprofen

Pirprofen is a nonsteroidal anti-inflammatory drug (NSAID) of the propionic acid derivative class, structurally related to ibuprofen, ketoprofen, and naproxen. It was developed by Ciba-Geigy and introduced in 1982 for the treatment of arthritis and pain, including rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, musculoskeletal disorders, and non-articular rheumatism. Pirprofen acts as a reversible inhibitor of prostaglandin synthetase (cyclooxygenase), thereby reducing inflammation and pain. It also possesses analgesic and antipyretic properties. The drug was withdrawn worldwide in 1990 due to reports of serious adverse effects including fatal liver toxicity[1][5][7][8].

Brand names

Rengasil

Other names

pirprofenepirprofeno2-(3-chloro-4-(3-pyrroli-1-yl)phenyl)propionic acid