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Piwei Peiyuan Formula is a traditional Chinese medicine (TCM) prescription used primarily for the treatment of chronic atrophic gastritis (CAG), including cases with intestinal metaplasia. It is composed of multiple herbal ingredients and has been utilized in clinical practice to attenuate the progression of CAG. The formula is believed to work through multi-targeted mechanisms typical of TCM prescriptions, such as regulating gastrointestinal function, reducing inflammation, and possibly modulating immune responses. Its mechanism involves holistic modulation rather than targeting a single molecular pathway[1][2]. Clinical studies have evaluated its efficacy and safety both alone and in combination with acupuncture for CAG[2].
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