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PK101-001 is a component of a fixed-dose combination anti-inflammatory drug currently being developed primarily for arthritis and osteoarthritis indications. The mechanism of action is currently undefined in public sources, and the molecule is considered a new molecular entity. PK101-001 is combined with PK101-002 in the investigational product known as PK 101 (developed by PMG Pharm/Pionex Management Group Pharm). Clinical development includes phase I studies for arthritis, and the combination PK 101 is in phase III trials for osteoarthritis. The precise active ingredient in PK101-001 is not disclosed in public databases, and no published data specify its pharmacological target or chemical nature. The larger combination (PK 101) includes a herbal extract (PG201) and celecoxib[1][3][7].
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