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pkcδ siRNA
- Development stage
- Preclinical
- Lead developer
- Santa Cruz Biotechnology
- Modality
- Chemically Modified siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Conjugated siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
- Administration
- Parenteral
01
Overview
PKCδ siRNA (Protein Kinase C delta small interfering RNA) is a research-grade gene-silencing tool designed to knock down the expression of Protein Kinase C delta (PKCδ), a serine/threonine kinase involved in apoptosis, cell proliferation, and stress signaling. It is widely used in preclinical research to study the role of PKCδ in various cancers, including HER2-positive breast cancer, melanoma, pancreatic cancer, and lung cancer, as well as in radioprotection. It is typically sold as a research reagent (such as by Santa Cruz Biotechnology under catalog number sc-36253) and is not currently developed as a clinical-stage therapeutic.
- Other names
- PKC delta siRNAPKCδ siRNAProtein Kinase C delta siRNA
02
Targets
PRKCD (Protein kinase C delta)
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