Drug intelligence / Profile preview

PlaCCine

Development stage
Unknown
Lead developer
IMUNON
Modality
DNA Vaccines → Plasmid DNA → DNA Therapeutics → Nucleic Acid Therapeutics, Prophylactic Vaccines → Vaccines & Immunotherapeutics
Administration
Intramuscular, Subcutaneous, Intradermal, Intranasal
01

Overview

PlaCCine is a **DNA vaccine platform** developed by IMUNON for prophylactic infectious disease vaccines. It uses proprietary mono- or multi-valent plasmid DNA formulated with a functionalized polymer and delivered via a non-viral vector system to protect the DNA from degradation and promote cellular uptake, enabling in vivo expression of encoded viral antigens and induction of immune responses. The platform is designed as a plug-and-play modality that can incorporate multiple antigens into a single plasmid; IMUNON has identified IMNN-101, a SARS-CoV-2 spike-targeting COVID-19 vaccine candidate, as the lead product emerging from this platform, with reported storage stability of up to one year at 4 degrees Celsius and up to two months at room temperature.

Other names
PLACCINE
02

Targets

SARS-CoV-2 spike

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