Drug intelligence / Profile preview

placebo + glimepiride

Development stage
Unknown
Modality
Small Molecules
Administration
Oral
01

Overview

This is a combination of a placebo (an inert substance with no pharmacological effect) and glimepiride, an oral antidiabetic medication. Glimepiride is a sulfonylurea that lowers blood glucose by stimulating insulin release from pancreatic beta cells and increasing the sensitivity of peripheral tissues to insulin. It is primarily used as an adjunct to diet and exercise for the management of type 2 diabetes mellitus in adults[1][2][3]. The inclusion of "placebo" in this combination typically indicates use in clinical trials, where one arm receives active drug plus placebo to maintain blinding or as part of a factorial design.

02

Targets

SUR1 (Sulfonylurea receptor 1)KCNJ11 (Atp-sensitive inward rectifier potassium channel 11)KCNJ1 (Kir1.1)ABCC9

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