Drug intelligence / Profile preview

placebo gel-Government Dental College and Research Institute, Bangalore-chronic periodontitis

Development stage
Unknown
Lead developer
Government Dental College and Research Institute
Modality
Hydrogel Systems → Drug Delivery Systems
Administration
Topical
01

Overview

This placebo gel is a control comparator used in randomized controlled trials conducted by the Government Dental College and Research Institute in Bangalore, India. It was specifically designed for studies evaluating the efficacy of locally delivered 1.2% atorvastatin gel as an adjunct to scaling and root planing for the treatment of chronic periodontitis, including mandibular degree II furcation defects and intrabony defects. The gel is formulated with a methylcellulose base and a biocompatible solvent, mirroring the physical properties and administration method of the active treatment but lacking the atorvastatin active ingredient. It is delivered subgingivally into periodontal pockets to maintain the double-blind nature of the clinical trials.

Other names
Placebo Gelplacebo control gel

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