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This placebo gel is a control comparator used in randomized controlled trials conducted by the Government Dental College and Research Institute in Bangalore, India. It was specifically designed for studies evaluating the efficacy of locally delivered 1.2% atorvastatin gel as an adjunct to scaling and root planing for the treatment of chronic periodontitis, including mandibular degree II furcation defects and intrabony defects. The gel is formulated with a methylcellulose base and a biocompatible solvent, mirroring the physical properties and administration method of the active treatment but lacking the atorvastatin active ingredient. It is delivered subgingivally into periodontal pockets to maintain the double-blind nature of the clinical trials.
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