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Drug intelligence / Profile preview
placental-derived autologous mesenchymal stem cells
- Development stage
- Phase 2
- Lead developer
- PLA Army Specialty Medical Center
- Modality
- Stem Cell Therapies → Cell Therapies
- Administration
- Intravenous
01
Overview
Placental-derived autologous mesenchymal stem cells (MSCs) are an experimental cell therapy being investigated for the treatment of bronchopulmonary dysplasia (BPD) in premature infants. The therapy involves isolating MSCs from the infant's own placenta, expanding them in vitro, and subsequently re-administering them to the same infant via intravenous infusion. These cells are hypothesized to exert therapeutic effects by migrating to injured lung tissue and secreting a variety of paracrine factors, including anti-inflammatory cytokines and growth factors, which promote tissue repair, reduce inflammation, and support angiogenesis in the developing neonatal lung.
- Other names
- autologous placental mesenchymal stem cellsplacenta-derived autologous MSCs
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