plant sterols + fish oil

**plant sterols + fish oil** is a combination dietary supplement consisting of plant sterols (including beta-sitosterol, campesterol, stigmasterol) and fish oil usually standardized to omega-3 fatty acids (EPA and DHA). The principal mechanism of plant sterols is to **inhibit intestinal absorption of cholesterol** via competition for incorporation into micelles and upregulation of enterocyte ATP-binding cassette transporters; this results in reduced serum LDL-cholesterol. The omega-3 fatty acids in fish oil **reduce triglycerides** via inhibition of hepatic VLDL synthesis and enhanced clearance of triglyceride-rich particles. Supplementation with both components has shown a synergistic effect, lowering LDL cholesterol and triglycerides simultaneously, and benefiting cardiovascular risk factors in people with hypercholesterolemia or metabolic syndrome. The supplement may also exert ancillary effects on inflammatory markers and glucose metabolism by modifying lipid profiles and insulin resistance.

Brand names

Beta-Sitosterol Plant Sterols SoftgelsCholesterol Support

Other names

plant sterols plus fish oilplant sterols and fish oilomega-3 + plant sterols