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plantain seed decoction
- Development stage
- Unknown
- Lead developer
- Shuguang Hospital
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Plantain seed decoction is a Traditional Chinese Medicine (TCM) aqueous preparation derived from the seeds of *Plantago asiatica* L. (known as Che Qian Zi). It has been specifically developed and clinically investigated by researchers at Shuguang Hospital affiliated to Shanghai University of TCM for the treatment of metabolic syndrome and its components, including type 2 diabetes mellitus, hypertension, and dyslipidemia. The decoction contains a variety of bioactive compounds, including phenylethanoid glycosides (such as acteoside and plantamajoside), iridoids (such as geniposidic acid), and flavonoids. Its therapeutic mechanism involves the regulation of glucose and lipid metabolism, improvement of insulin sensitivity, and potential diuretic effects that contribute to blood pressure management. Clinical studies conducted at Shuguang Hospital have evaluated its efficacy in improving glycemic control, lipid profiles, and waist circumference in patients with metabolic disturbances.
- Other names
- Cheqianzi decoctionSemen Plantaginis decoctionPlantago asiatica seed decoction
02
Targets
PPARG (Peroxisome proliferator-activated receptor gamma)Sucrase-IsomaltaseAMPK (Adenosine monophosphate–activated protein kinase)
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