Drug intelligence / Profile preview

plasma protein fraction human

Development stage
Approved
Lead developer
Grifols
Modality
Recombinant Proteins and Enzymes
Administration
Intravenous
01

Overview

**Plasma protein fraction human** is a sterile, plasma-derived colloid solution for intravenous infusion composed primarily of human albumin with smaller quantities of alpha and beta globulins. It expands intravascular plasma volume through the colloid osmotic pressure of its protein content and is used for plasma-volume replacement in shock caused by burns, crushing injuries, abdominal emergencies, hemorrhage, and other settings with predominant plasma-fluid loss. The currently labeled United States product, **Plasmanate**, contains 5 g selected plasma proteins per 100 mL and is approximately iso-oncotic and isotonic with normal plasma. ([dailymed.nlm.nih.gov](https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=679bbaf2-b082-5948-8400-ece5340eabc1))

Brand names
Plasmanate
Other names
human plasma protein fractionplasma protein fractionplasma protein

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