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platelet-derived growth factor concentrate freeze-dried
- Development stage
- Unknown
- Lead developer
- CellSource
- Administration
- Parenteral
01
Overview
Platelet-Derived Growth Factor Concentrate Freeze-Dried (PFC-FD™) is an autologous, acellular, lyophilized biologic derived from platelet-rich plasma (PRP), developed by CellSource Co., Ltd. It is produced by processing a patient's own blood to isolate PRP, activating platelets to release growth factors (including PDGF, VEGF, TGF-β, EGF, bFGF, IGF, and HGF), filtering out cellular components, and freeze-drying the resulting concentrate. This process allows for stable room-temperature storage and a higher concentration of growth factors compared to standard PRP. It is primarily investigated for intra-ovarian injection to treat diminished ovarian reserve (DOR) and premature ovarian insufficiency (POI) by stimulating tissue regeneration and folliculogenesis.
- Brand names
- PFC-FD
- Other names
- platelet-derived factor concentrate freeze-dry
02
Targets
EGFR (Epidermal growth factor receptor)FGFR (Fibroblast growth factor receptor)IGF-1R (Insulin-like growth factor 1 receptor)MET (Mesenchymal-epithelial transition factor receptor)PDGFRA (Platelet-derived growth factor receptor alpha)PDGFRB (Platelet-derived growth factor receptor beta)TGFBR (TGF-beta receptor)VEGFR (VEGFR family)
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