platelet-rich plasma (Menoufia University)

Platelet-rich plasma (PRP) is an autologous biologic therapy derived from a patient's own blood through centrifugation, which concentrates platelets and their associated growth factors. In the clinical context investigated by Menoufia University, PRP is used as a regenerative treatment for mild-to-moderate idiopathic carpal tunnel syndrome. The mechanism involves the release of growth factors—such as platelet-derived growth factor (PDGF), transforming growth factor-beta (TGF-β), and vascular endothelial growth factor (VEGF)—which are thought to promote axon regeneration, reduce perineural inflammation, and enhance the neurological recovery of the compressed median nerve. This treatment is typically administered as a single ultrasound-guided injection into the carpal tunnel, serving as an alternative to corticosteroid injections or surgical intervention.

Other names

PRPautologous platelet-rich plasma